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Links to each article's PubMed entry or journal website are included below. If you are unable to retrieve an article in this way, please request a copy by email from
jjziarek(at)indiana.edu
before indiana university
26. Hitchinson B., Eby J.M., Gao X., Guite-Vinet F.,
Ziarek J.J.
, Abdelkarim H., Lee Y., Okamoto Y., Shikano S., Majetschak M., Heveker N., Volkman B.F., Tarasova N.I. & Gaponenko, V. 2018. Biased antagonism of CXCR4 avoids antagonist tolerance. Science Signaling, 11:eaat2214.
25.
Ziarek, J.J.
, Baptista, D. & Wagner, G. 2018. Recent developments in solution NMR-based molecular biology. Journal of Molecular Medicine, 96:1-8
.
24. Chhabra, S., Fischer, P., Takeuchi, K., Dubey, A.,
Ziarek, J.J.
, Boeszoermenyi, A., Mathieu, D., Bermel, W., Davey, N.E., Wagner, G. & Arthanari, H. A. 2018. 15N Detection Harnesses the Slow Relaxation Property of Nitrogen: Delivering Enhanced Resolution for Intrinsically Disordered Proteins. Proceedings of the National Academy of Sciences of the United States of America, 115(8):E1710-1719.
23.
Ziarek, J.J.
, Kleist, A.B, London, N., Raveh, B., Montpas, N., Bonneterre, J., St-Onge, G., DiCosmo-Ponticello, C.J., Koplinski, C.A., Roy, I., Stephens, B., Thelen, S., Veldkamp, C.T., Coffman, F.D., Cohen, M.C., Dwinell, M.B., Thelen, M., Peterson, F.C., Heveker, N. & Volkman, B.F. 2017. Structural basis for chemokine recognition of a G protein-coupled receptor and implications for receptor activation. Science Signaling, 10:eaah5756.
22. Kleist, A.B., Getschman, A.E.,
Ziarek, J.J.
, Nevins, A.M., Gauthier, P-A., Chevigne, A., Szpakowska, M. & Volkman, B.F. 2016. New paradigms in chemokine receptor signal transduction: moving beyond the two-site model. Biochemical Pharmacology, 114:53-68.
21. Nihongi, A.,
Ziarek, J.J.
Uttieri, M., Sandulli, R., Zambianchi, E. & Strickler, J.R. 2016. Behavioral interseasonal adaptations in Daphnia pulicaria (Crustacea: Cladocera) as induced by predation infochemicals. Aquatic Ecology, doi:10.1007/s10452-016-9585-0.
20. Smith, E., Liu, Y., Getschman, A.E., Peterson, F.C.,
Ziarek, J.J.
, Li, R., Volkman, B.F. & Chen, Y. 2014. Structural analysis of a novel small molecule ligand bound to the CXCL12 chemokine. Journal of Medicinal Chemistry, 57(22):9693-9699.
19. Wommack, A.J.,
Ziarek, J.J.
, Tomaras, J., Chileveru, H.R., Zhang, Y., Wagner, G. & Nolan, E.M. 2014. Discovery and characterization of a disulfide-locked C2-symmetric defensin peptide. Journal of the American Chemical Society, 136(39):13494-13497.
18. Verkaar, F., van Offenbeek, J., van der Lee, M.M.C., van Lith, L.H.C.J., Watts, A.O., Rops, A.L.W.M.M., Aguilar, D.C.,
Ziarek, J.J.
, van der Vlag, J., Handel, T.M., Volkman, B.F., Proudfoot, A.E.I., Vischer, H.F., Zaman, G.J.R., & Smit, M.J. 2014. Chemokine cooperativity is caused by competitive glycosaminoglycan binding. Journal of Immunology, 192(8):3908-3914.
17.
Ziarek, J.J.
★, Getschman, A.E.★, Butler, S.J., Taleski, D., Stephens, B., Kufareva, I., Handel, T.M., Payne, R.J. & Volkman, B.F. 2013. Sulfopeptide probes of the CXCR4/CXCL12 interface reveal oligomer-specific contacts and chemokine allostery. ACS Chemical Biology, 8:1955-1963. ★
Equal contributors
.
16.
Ziarek, J.J.
, Veldkamp, C.T., Zhang, F. Murray, N.J., Kartz, G.A., Liang, X., Su, J., Baker, J.E., Lindhardt, R.J. & Volkman, B.F. 2013. Heparin Oligosaccharides Inhibit Chemokine (CXC Motif) Ligand 12 (CXCL12) Cardioprotection by Binding Orthogonal to the Dimerization Interface, Promoting Oligomerization, and Competing with the Chemokine (CXC Motif) Receptor 4 (CXCR4) N Terminus. Journal of Biological Chemistry, 288:737-746.
15. Luna, R.E.★, Akabayov, S.R.★,
Ziarek, J.J.
★ & Wagner, G. 2013. Examining weak protein-protein interactions in start codon recognition via nuclear magnetic resonance spectroscopy. FEBS Journal, 281(8):1965-1973. ★
Equal contributors
.
14.
Ziarek, J.J.
★, Liu, Y.★, Smith, E., Chen, J., Peterson, F.C., Zhang, G., Yu, Y., Chen, Y., Volkman, B.F. & Li, R. 2012. Fragment-based optimization of small molecule CXCL12 inhibitors for antagonizing the CXCL12/CXCR4 interaction. Current Topics in Medicinal Chemistry, 12:2727-2740
.
★
Equal contributors.
13.
Ziarek, J.J.
& Volkman, B.F. 2012. NMR in the analysis of functional chemokine interactions and drug discovery. Drug Discovery Today: Technologies, 9:e293-e299.
12. Takekoshi, T.,
Ziarek, J.J.
, Volkman, B.F. & Hwang, S.T. 2012. A locked, dimeric CXCL12 variant effectively inhibits pulmonary metastasis of CXCR4-expressing melanoma cells due to enhanced serum stability
.
Molecular Cancer Therapeutics, 11:2516-2525.
11. Mysinger, M.M.★, Weiss, D.R.★,
Ziarek, J.J.
★, Gravel, S., Doak, A.K., Karpiak, J., Heveker, N., Shoichet, B.K. & Volkman, B.F. 2012. Structure-based ligand discovery for chemokine receptor CXCR4. Proceedings of the National Academy of Sciences of the United States of America, 109: 5517-5522. ★
Equal contributors.
10. Love, M., Sandberg, J.L.,
Ziarek, J.J.
, Rode, R.R., Gerarden, K.P., Jensen, D.R., McCastlin, D., Peterson, F.C. & Veldkamp, C.T. 2012. Solution structure of CCL21 and identification of a putative CCR7 binding site. Biochemistry, 51(3): 733-735.
9.
Ziarek, J.J.
, Peterson, F.C., Lytle, B.L. & Volkman, B.F. 2011. Chapter ten: Binding site identification and structure determination of protein-ligand complexes by NMR. Methods in Enzymology, 493:241-275.
8. Drury, L.D.★,
Ziarek, J.J.
★, Gravel, S., Veldkamp, C.T., Takekoshi, T., Hwang, S.T., Heveker, N., Volkman, B.F. & Dwinell, M.B. 2011. Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways. Proceedings of the National Academy of Sciences of the United States of America, 108: 17655-17660. ★
Equal contributors
.
7. Saini, V., Staren, D.M.,
Ziarek, J.J.
, Nashaat, Z.N., Campbell, E.M., Volkman, B.F., Marchese, A. & Majetschak, M. 2011. The CXC chemokine receptor 4 ligands ubiquitin and stromal-cell derived factor-1α function through distinct receptor interactions. Journal of Biological Chemistry, 286: 33466-33477.
6.
Ziarek, J.J.
, Heroux, M.S., Veldkamp, C.T., Peterson, F.C. & Volkman, B.F. 2011. Sulfotyrosine recognition as marker for druggable sites in the extracellular space. International Journal of Molecular Sciences, 12(6), 3740-3756.
5.
Ziarek, J.J.
, Nihongi, A., Nagai, T., Uttieri, M., Zambianchi, E., & Stricker, J.R. 2011. Seasonal adaptations of
Daphnia pulicaria
swimming behaviour: the effect of water temperature. Hydrobiologia, 661: 317-327.
4. Nihongi, A.,
Ziarek, J.J.
, Nagai, T., Uttieri, M., Zambianchi, E. & Strickler, J.R. 2011. Daphnia pulicaria hijacked by Vibrio cholera: Altered swimming behaviour and predation risk Implications. In: Zooplankton and Phytoplankton. Ed: Katell, G. Nova Science Publishers.
3. Veldkamp, C.T.,
Ziarek, J.J.
, Peterson, F.C., Chen, Y. & Volkman, B.F. 2010. Targeting SDF-1/CXCL12 with a ligand that prevents activation of CXCR4 through structure based drug design. Journal of the American Chemical Society
,
132: 7242-7243.
2. Veldkamp, C.T.,
Ziarek, J.J.
, Su, J., Basnet, H., Lennertz, R., Weiner, J.J., Peterson, F.C., Baker, J.E. & Volkman, B.F. 2009. Monomeric structure of the cardioprotective chemokine SDF-1/CXCL12. Protein Science, 18:1359-1369.
1. Strickler, J.R., Udvadia, A.J., Marino, J., Radabaugh, N.,
Ziarek, J.J.
, & Nihongi, A. 2005. Visibility as a factor in the copepod – planktivorous fish relationship. Scientia Marina
,
69(Suppl. 1):111-124.
research
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former members
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