ziarek lab @ northwestern university
  • research
  • members
    • former members
  • publications
    • as a trainee
  • news
  • funding
  • contact
    • Pharmacology Department
Links to each article's PubMed entry or journal website are included below.  If you are unable to retrieve an article in this way, please request a copy by email from joshua.ziarek(at)northwestern.edu
the modern age
15.  Shriver, T.J., Kahraman, K., Pan, M., Dag, C., Tonelli, M., Robson, S.A. & J.J. Ziarek. 2025. Intrinsic conformational equilibria position arrestin-2 for activation. bioRxiv preprint

14.  Bower, J.B., Van der Velden, W.J.C., Gomez, K.P., Pan, M., Bumbak, F., Vaidehi, N. & J.J. Ziarek. 2025. Stabilization versus flexibility: detergent-dependent trade-offs in neurotensin receptor 1 GPCR ensembles. bioRxiv preprint
​
13. Roy, S.M., Acquarone, E., Argyrousi, E.K., Zhang, H., Staniszewski, A., Inoue, A., Ziarek, J.J., Arancio, O. & D.M. Watterson. 2025. Optimized 5-HT2b inhibitors for neuropsychiatric syndromes with cognitive dysfunction. Alzheimer's & Dementia, 11(1):e70073.

12.  Rai, R., Dawodu, O.I., Meng, J., Johnson, S.M., Vilseck, J.Z., Kelley, M.R., Ziarek, J.J., & M.M Georgiadis. 2025. Chemically induced partial unfolding of the multifunctional apurinic/apyrimidinic endonuclease I. Protein Science, 34(6):e70148.

11. Manley, O., Shriver, T.J., Xu, T., Melendrez, I.A., Palacios, P.M., Robson, S.A., Guo, Y., Kelleher, N.L., Ziarek, J.J. & A.C. Rosenzweig. 2024. A multi-iron enzyme installs copper-binding oxazolonethioamide pairs on a nontypeable Haemophilus influenzae virulence factor. Proceedings of the National Academy of Sciences, 121 (28) e2408092121.

10.  Bower, J.B., Robson, S.A. & Ziarek, J.J. 2024. Insights on the GPCR helix 8 solution structure and orientation using a neurotensin receptor 1 peptide. Protein Science, 33(6):e4976.

9. Kahrama, K., Robson, S.A., Gocenler, O., Yenici, C.M., Tozkoparan, C.D., Klein, J.M., Haas, A.L., Ziarek, J.J.*, & C. Dag*. 2024. Characterizing the monomer-dimer equilibrium of UbcH8/Ube2L6: A combined SAXS and NMR study. ACS Omega. *Co-corresponding authors.

8. Bumbak, F., Bower, J.B., Zemmer, S.C., Inoue, A., Paniagua, J.C., Pons, M., Yan, F., Ford, J., Wu, H., Robson, S.A., Bathgate, R.A.D., Scott, D.J., Gooley, P.R. & J.J. Ziarek. 2023. Stabilization of pre-existing neurotensin receptor conformational states by β-arrestin-1 and the biased allosteric modulator ML314. Nature Communications, 14:3328.

7. Bumbak, F., Pons, M., Inoue, A., Paniagua, J.C., Yan, F., Wu, H., Robson, S.A., Bathgate, R.A.D., Scott, D.J., Gooley, P.R. & J.J. Ziarek. 2023. Ligands tune the global and local motions of neurotensin receptor 1 (NTS1). Cell Reports, 42(1):112015.

6. Dixon, A.D., Robson, S.A., Trinidad, J.C. & J.J. Ziarek. 2022. A method for Selective 19F-labeling Absent of Probe Sequestration (SLAPS). Protein Science, 31:e4454.

5. Dixon, A.D., Inoue, A., Robson, S.A., Culhane,  K.J., Trinidad, J.C., Sivaramakrishnan, S., Bumbak, F. & J.J. Ziarek. 2022. The effect of ligands and transducers on the Neurotensin receptor 1 (NTS1) conformational ensemble. Journal of the American Chemical Society, 144(23):10241-10250.

4. Melland, H., Bumbak, F., Kolesnik-Taylor, A., Ng-Cordell, E., John, A., Constantinou, P., Joss, S., Larsen, M., Fagerberg, C., Thies, J., Emslie, F., Willemsen, M., Kleefstra, T., Pfundt, R., Barrick, R., Chang, R., Loong, L., Alfadhel, M., van der Smagt, J., Nizon, M., Kurian, M., Scott, D.J., Ziarek, J.J., Gordon, S. & K. Baker. 2022. Expanding the genotype and phenotype spectrum of SYT1-associated neurodevelopmental disorder. Genetics in Medicine, 24(4):880-893.

3. Robson, S.A., Dağ, Ç., Wu, H. & J.J. Ziarek. 2021. TRACT revisited: An Algebraic Solution for Determining Overall Rotational Correlation Times from Cross-Correlated Relaxation Rates. Journal of Biomolecular NMR, 75(8-9):293-302.

2. Chamness, L.M., Zelt, N.B., Harrington, H.R., Kuntz, C.P., Bender, B.J., Penn, W.D., Ziarek, J.J., Meiler, J. & J.P. Schlebach. 2021. Molecular Basis for the Evolved Instability of a Human G-Protein Coupled Receptor. Cell Reports, 37(8):110046-110058.

1.  Gruenhagen, T., Ziarek, J.J. & J.P. Schlebach. 2018. Bicelle Size Modulates the Rate of Bacteriorhodopsin Folding. Protein Science, 27(6):1109-1112.
  • research
  • members
    • former members
  • publications
    • as a trainee
  • news
  • funding
  • contact
    • Pharmacology Department