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Links to each article's PubMed entry or journal website are included below. If you are unable to retrieve an article in this way, please request a copy by email from
joshua.ziarek(at)northwestern.edu
the modern age
15. Shriver, T.J., Kahraman, K., Pan, M., Dag, C., Tonelli, M., Robson, S.A. &
J.J.
Ziarek.
2025. Intrinsic conformational equilibria position arrestin-2 for activation.
bioRxiv
preprint
14.
Bower, J.B., Van der Velden, W.J.C., Gomez, K.P., Pan, M., Bumbak, F., Vaidehi, N. &
J.J.
Z
iarek.
2025. Stabilization versus flexibility: detergent-dependent trade-offs in neurotensin receptor 1 GPCR ensembles.
bioRxiv
preprint
13. Roy, S.M., Acquarone, E., Argyrousi, E.K., Zhang, H., Staniszewski, A., Inoue, A.,
Ziarek, J.J.
, Arancio, O. & D.M. Watterson. 2025. Optimized 5-HT2b inhibitors for neuropsychiatric syndromes with cognitive dysfunction.
Alzheimer's & Dementia
, 11(1):e70073.
12. Rai, R., Dawodu, O.I., Meng, J., Johnson, S.M., Vilseck, J.Z., Kelley, M.R.,
Ziarek, J.J.
, & M.M Georgiadis. 2025. Chemically induced partial unfolding of the multifunctional apurinic/apyrimidinic endonuclease I.
Protein Science
, 34(6):e70148.
11. Manley, O., Shriver, T.J., Xu, T., Melendrez, I.A., Palacios, P.M., Robson, S.A., Guo, Y., Kelleher, N.L.,
Ziarek, J.J.
& A.C. Rosenzweig. 2024. A multi-iron enzyme installs copper-binding oxazolonethioamide pairs on a nontypeable Haemophilus influenzae virulence factor.
Proceedings of the National Academy of Sciences,
121
(
28
)
e2408092121.
10. Bower, J.B., Robson, S.A. &
Ziarek, J.J.
2024. Insights on the GPCR helix 8 solution structure and orientation using a neurotensin receptor 1 peptide.
Protein Science
,
33(6):e4976
.
9. Kahrama, K., Robson, S.A., Gocenler, O., Yenici, C.M., Tozkoparan, C.D., Klein, J.M., Haas, A.L.,
Ziarek, J.J.*
, & C. Dag*. 2024. Characterizing the monomer-dimer equilibrium of UbcH8/Ube2L6: A combined SAXS and NMR study.
ACS Omega
.
*Co-corresponding authors.
8. Bumbak, F., Bower, J.B., Zemmer, S.C., Inoue, A., Paniagua, J.C., Pons, M., Yan, F., Ford, J., Wu, H., Robson, S.A., Bathgate, R.A.D., Scott, D.J., Gooley, P.R. &
J.J. Ziarek
. 2023. Stabilization of pre-existing neurotensin receptor conformational states by β-arrestin-1 and the biased allosteric modulator ML314.
Nature Communications
,
14:3328
.
7
. Bumbak, F., Pons, M., Inoue, A., Paniagua, J.C., Yan, F., Wu, H., Robson, S.A., Bathgate, R.A.D., Scott, D.J., Gooley, P.R. &
J.J. Ziarek
. 2023. Ligands tune the global and local motions of neurotensin receptor 1 (NTS1).
Cell Reports
,
42(1):112015.
6
. Dixon, A.D.,
Robson, S.A., Trinidad
, J.C. &
J.J. Ziarek
. 2022. A method for Selective 19F-labeling Absent of Probe Sequestration (SLAPS).
Protein Science
, 31:e4454.
5. Dixon, A.D., Inoue, A., Robson, S.A.,
Culhane
, K.J.,
Trinidad
, J.C.,
Sivaramakrishnan, S.
,
Bumbak
, F. &
J.J. Ziarek
. 2022. The effect of ligands and transducers on the Neurotensin receptor 1 (NTS1) conformational ensemble.
Journal of the American Chemical Society
,
144(23):10241-10250.
4. Melland, H., Bumbak, F., Kolesnik-Taylor, A., Ng-Cordell, E., John, A., Constantinou, P., Joss, S., Larsen, M., Fagerberg, C., Thies, J., Emslie, F., Willemsen, M., Kleefstra, T., Pfundt, R., Barrick, R., Chang, R., Loong, L., Alfadhel, M., van der Smagt, J., Nizon, M., Kurian, M., Scott, D.J.,
Ziarek, J.J.
, Gordon, S. & K. Baker. 2022. Expanding the genotype and phenotype spectrum of SYT1-associated neurodevelopmental disorder.
Genetics in Medicine
, 24(4):880-893.
3. Robson, S.A., Dağ, Ç., Wu, H. &
J.J. Ziarek
.
2021. TRACT revisited: An Algebraic Solution for Determining Overall Rotational Correlation Times from Cross-Correlated Relaxation Rates.
Journal of Biomolecular NMR
,
75(8-9):293-302.
2. Chamness, L.M., Zelt, N.B., Harrington, H.R., Kuntz, C.P., Bender, B.J., Penn, W.D.,
Ziarek, J.J.
, Meiler, J. & J.P. Schlebach. 2021. Molecular Basis for the Evolved Instability of a Human G-Protein Coupled Receptor.
Cell Reports
, 37(8):110046-110058.
1. Gruenhagen, T.,
Ziarek, J.J.
& J.P. Schlebach. 2018. Bicelle Size Modulates the Rate of Bacteriorhodopsin Folding.
Protein Science
,
27(6):1109-1112
.
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