Links to each article's PubMed entry or journal website are included below. If you are unable to retrieve an article in this way, please request a copy by email from jjziarek@indiana.edu
before indiana university
26. Hitchinson B, Eby JM, Gao X, Guite-Vinet F, Ziarek JJ, Abdelkarim H, Lee Y, Okamoto Y, Shikano S, Majetschak M, Heveker N, Volkman BF, Tarasova NI & Gaponenko, V. 2018. Biased antagonism of CXCR4 avoids antagonist tolerance. Science Signaling, 11:eaat2214.
25. Ziarek, J.J., Baptista, D. & Wagner, G. 2018. Recent developments in solution NMR-based molecular biology. Journal of Molecular Medicine, 96:1-8.
24. Chhabra, S., Fischer, P., Takeuchi, K., Dubey, A., Ziarek, J.J., Boeszoermenyi, A., Mathieu, D., Bermel, W., Davey, N.E., Wagner, G. & Arthanari, H. A. 2018. 15N Detection Harnesses the Slow Relaxation Property of Nitrogen: Delivering Enhanced Resolution for Intrinsically Disordered Proteins. Proceedings of the National Academy of Sciences of the United States of America, 115(8):E1710-1719.
23. Ziarek, J.J., Kleist, A.B, London, N., Raveh, B., Montpas, N., Bonneterre, J., St-Onge, G., DiCosmo-Ponticello, C.J., Koplinski, C.A., Roy, I., Stephens, B., Thelen, S., Veldkamp, C.T., Coffman, F.D., Cohen, M.C., Dwinell, M.B., Thelen, M., Peterson, F.C., Heveker, N. & Volkman, B.F. 2017. Structural basis for chemokine recognition of a G protein-coupled receptor and implications for receptor activation. Science Signaling, 10:eaah5756.
22. Kleist, A.B., Getschman, A.E., Ziarek, J.J., Nevins, A.M., Gauthier, P-A., Chevigne, A., Szpakowska, M. & Volkman, B.F. 2016. New paradigms in chemokine receptor signal transduction: moving beyond the two-site model. Biochemical Pharmacology, 114:53-68.
21. Nihongi, A., Ziarek, J.J. Uttieri, M., Sandulli, R., Zambianchi, E. & Strickler, J.R. 2016. Behavioral interseasonal adaptations in Daphnia pulicaria (Crustacea: Cladocera) as induced by predation infochemicals. Aquatic Ecology, doi:10.1007/s10452-016-9585-0.
20. Smith, E., Liu, Y., Getschman, A.E., Peterson, F.C., Ziarek, J.J., Li, R., Volkman, B.F. & Chen, Y. 2014. Structural analysis of a novel small molecule ligand bound to the CXCL12 chemokine. Journal of Medicinal Chemistry, 57(22):9693-9699.
19. Wommack, A.J., Ziarek, J.J., Tomaras, J., Chileveru, H.R., Zhang, Y., Wagner, G. & Nolan, E.M. 2014. Discovery and characterization of a disulfide-locked C2-symmetric defensin peptide. Journal of the American Chemical Society, 136(39):13494-13497.
18. Verkaar, F., van Offenbeek, J., van der Lee, M.M.C., van Lith, L.H.C.J., Watts, A.O., Rops, A.L.W.M.M., Aguilar, D.C., Ziarek, J.J., van der Vlag, J., Handel, T.M., Volkman, B.F., Proudfoot, A.E.I., Vischer, H.F., Zaman, G.J.R., & Smit, M.J. 2014. Chemokine cooperativity is caused by competitive glycosaminoglycan binding. Journal of Immunology, 192(8):3908-3914.
17. Ziarek, J.J.★, Getschman, A.E.★, Butler, S.J., Taleski, D., Stephens, B., Kufareva, I., Handel, T.M., Payne, R.J. & Volkman, B.F. 2013. Sulfopeptide probes of the CXCR4/CXCL12 interface reveal oligomer-specific contacts and chemokine allostery. ACS Chemical Biology, 8:1955-1963. ★Equal contributors.
16. Ziarek, J.J., Veldkamp, C.T., Zhang, F. Murray, N.J., Kartz, G.A., Liang, X., Su, J., Baker, J.E., Lindhardt, R.J. & Volkman, B.F. 2013. Heparin Oligosaccharides Inhibit Chemokine (CXC Motif) Ligand 12 (CXCL12) Cardioprotection by Binding Orthogonal to the Dimerization Interface, Promoting Oligomerization, and Competing with the Chemokine (CXC Motif) Receptor 4 (CXCR4) N Terminus. Journal of Biological Chemistry, 288:737-746.
15. Luna, R.E.★, Akabayov, S.R.★, Ziarek, J.J.★ & Wagner, G. 2013. Examining weak protein-protein interactions in start codon recognition via nuclear magnetic resonance spectroscopy. FEBS Journal, 281(8):1965-1973. ★Equal contributors.
14. Ziarek, J.J.★, Liu, Y.★, Smith, E., Chen, J., Peterson, F.C., Zhang, G., Yu, Y., Chen, Y., Volkman, B.F. & Li, R. 2012. Fragment-based optimization of small molecule CXCL12 inhibitors for antagonizing the CXCL12/CXCR4 interaction. Current Topics in Medicinal Chemistry, 12:2727-2740. ★Equal contributors.
13. Ziarek, J.J. & Volkman, B.F. 2012. NMR in the analysis of functional chemokine interactions and drug discovery. Drug Discovery Today: Technologies, 9:e293-e299.
12. Takekoshi, T., Ziarek, J.J., Volkman, B.F. & Hwang, S.T. 2012. A locked, dimeric CXCL12 variant effectively inhibits pulmonary metastasis of CXCR4-expressing melanoma cells due to enhanced serum stability. Molecular Cancer Therapeutics, 11:2516-2525.
11. Mysinger, M.M.★, Weiss, D.R.★, Ziarek, J.J.★, Gravel, S., Doak, A.K., Karpiak, J., Heveker, N., Shoichet, B.K. & Volkman, B.F. 2012. Structure-based ligand discovery for chemokine receptor CXCR4. Proceedings of the National Academy of Sciences of the United States of America, 109: 5517-5522. ★Equal contributors.
10. Love, M., Sandberg, J.L., Ziarek, J.J., Rode, R.R., Gerarden, K.P., Jensen, D.R., McCastlin, D., Peterson, F.C. & Veldkamp, C.T. 2012. Solution structure of CCL21 and identification of a putative CCR7 binding site. Biochemistry, 51(3): 733-735.
9. Ziarek, J.J., Peterson, F.C., Lytle, B.L. & Volkman, B.F. 2011. Chapter ten: Binding site identification and structure determination of protein-ligand complexes by NMR. Methods in Enzymology, 493:241-275.
8. Drury, L.D.★, Ziarek, J.J.★, Gravel, S., Veldkamp, C.T., Takekoshi, T., Hwang, S.T., Heveker, N., Volkman, B.F. & Dwinell, M.B. 2011. Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways. Proceedings of the National Academy of Sciences of the United States of America, 108: 17655-17660. ★Equal contributors.
7. Saini, V., Staren, D.M., Ziarek, J.J., Nashaat, Z.N., Campbell, E.M., Volkman, B.F., Marchese, A. & Majetschak, M. 2011. The CXC chemokine receptor 4 ligands ubiquitin and stromal-cell derived factor-1α function through distinct receptor interactions. Journal of Biological Chemistry, 286: 33466-33477.
6. Ziarek, J.J., Heroux, M.S., Veldkamp, C.T., Peterson, F.C. & Volkman, B.F. 2011. Sulfotyrosine recognition as marker for druggable sites in the extracellular space. International Journal of Molecular Sciences, 12(6), 3740-3756.
5. Ziarek, J.J., Nihongi, A., Nagai, T., Uttieri, M., Zambianchi, E., & Stricker, J.R. 2011. Seasonal adaptations of Daphnia pulicaria swimming behaviour: the effect of water temperature. Hydrobiologia, 661: 317-327.
4. Nihongi, A., Ziarek, J.J., Nagai, T., Uttieri, M., Zambianchi, E. & Strickler, J.R. 2011. Daphnia pulicaria hijacked by Vibrio cholera: Altered swimming behaviour and predation risk Implications. In: Zooplankton and Phytoplankton. Ed: Katell, G. Nova Science Publishers.
3. Veldkamp, C.T., Ziarek, J.J., Peterson, F.C., Chen, Y. & Volkman, B.F. 2010. Targeting SDF-1/CXCL12 with a ligand that prevents activation of CXCR4 through structure based drug design. Journal of the American Chemical Society, 132: 7242-7243.
2. Veldkamp, C.T., Ziarek, J.J., Su, J., Basnet, H., Lennertz, R., Weiner, J.J., Peterson, F.C., Baker, J.E. & Volkman, B.F. 2009. Monomeric structure of the cardioprotective chemokine SDF-1/CXCL12. Protein Science, 18:1359-1369.
1. Strickler, J.R., Udvadia, A.J., Marino, J., Radabaugh, N., Ziarek, J.J., & Nihongi, A. 2005. Visibility as a factor in the copepod – planktivorous fish relationship. Scientia Marina, 69(Suppl. 1):111-124.
25. Ziarek, J.J., Baptista, D. & Wagner, G. 2018. Recent developments in solution NMR-based molecular biology. Journal of Molecular Medicine, 96:1-8.
24. Chhabra, S., Fischer, P., Takeuchi, K., Dubey, A., Ziarek, J.J., Boeszoermenyi, A., Mathieu, D., Bermel, W., Davey, N.E., Wagner, G. & Arthanari, H. A. 2018. 15N Detection Harnesses the Slow Relaxation Property of Nitrogen: Delivering Enhanced Resolution for Intrinsically Disordered Proteins. Proceedings of the National Academy of Sciences of the United States of America, 115(8):E1710-1719.
23. Ziarek, J.J., Kleist, A.B, London, N., Raveh, B., Montpas, N., Bonneterre, J., St-Onge, G., DiCosmo-Ponticello, C.J., Koplinski, C.A., Roy, I., Stephens, B., Thelen, S., Veldkamp, C.T., Coffman, F.D., Cohen, M.C., Dwinell, M.B., Thelen, M., Peterson, F.C., Heveker, N. & Volkman, B.F. 2017. Structural basis for chemokine recognition of a G protein-coupled receptor and implications for receptor activation. Science Signaling, 10:eaah5756.
22. Kleist, A.B., Getschman, A.E., Ziarek, J.J., Nevins, A.M., Gauthier, P-A., Chevigne, A., Szpakowska, M. & Volkman, B.F. 2016. New paradigms in chemokine receptor signal transduction: moving beyond the two-site model. Biochemical Pharmacology, 114:53-68.
21. Nihongi, A., Ziarek, J.J. Uttieri, M., Sandulli, R., Zambianchi, E. & Strickler, J.R. 2016. Behavioral interseasonal adaptations in Daphnia pulicaria (Crustacea: Cladocera) as induced by predation infochemicals. Aquatic Ecology, doi:10.1007/s10452-016-9585-0.
20. Smith, E., Liu, Y., Getschman, A.E., Peterson, F.C., Ziarek, J.J., Li, R., Volkman, B.F. & Chen, Y. 2014. Structural analysis of a novel small molecule ligand bound to the CXCL12 chemokine. Journal of Medicinal Chemistry, 57(22):9693-9699.
19. Wommack, A.J., Ziarek, J.J., Tomaras, J., Chileveru, H.R., Zhang, Y., Wagner, G. & Nolan, E.M. 2014. Discovery and characterization of a disulfide-locked C2-symmetric defensin peptide. Journal of the American Chemical Society, 136(39):13494-13497.
18. Verkaar, F., van Offenbeek, J., van der Lee, M.M.C., van Lith, L.H.C.J., Watts, A.O., Rops, A.L.W.M.M., Aguilar, D.C., Ziarek, J.J., van der Vlag, J., Handel, T.M., Volkman, B.F., Proudfoot, A.E.I., Vischer, H.F., Zaman, G.J.R., & Smit, M.J. 2014. Chemokine cooperativity is caused by competitive glycosaminoglycan binding. Journal of Immunology, 192(8):3908-3914.
17. Ziarek, J.J.★, Getschman, A.E.★, Butler, S.J., Taleski, D., Stephens, B., Kufareva, I., Handel, T.M., Payne, R.J. & Volkman, B.F. 2013. Sulfopeptide probes of the CXCR4/CXCL12 interface reveal oligomer-specific contacts and chemokine allostery. ACS Chemical Biology, 8:1955-1963. ★Equal contributors.
16. Ziarek, J.J., Veldkamp, C.T., Zhang, F. Murray, N.J., Kartz, G.A., Liang, X., Su, J., Baker, J.E., Lindhardt, R.J. & Volkman, B.F. 2013. Heparin Oligosaccharides Inhibit Chemokine (CXC Motif) Ligand 12 (CXCL12) Cardioprotection by Binding Orthogonal to the Dimerization Interface, Promoting Oligomerization, and Competing with the Chemokine (CXC Motif) Receptor 4 (CXCR4) N Terminus. Journal of Biological Chemistry, 288:737-746.
15. Luna, R.E.★, Akabayov, S.R.★, Ziarek, J.J.★ & Wagner, G. 2013. Examining weak protein-protein interactions in start codon recognition via nuclear magnetic resonance spectroscopy. FEBS Journal, 281(8):1965-1973. ★Equal contributors.
14. Ziarek, J.J.★, Liu, Y.★, Smith, E., Chen, J., Peterson, F.C., Zhang, G., Yu, Y., Chen, Y., Volkman, B.F. & Li, R. 2012. Fragment-based optimization of small molecule CXCL12 inhibitors for antagonizing the CXCL12/CXCR4 interaction. Current Topics in Medicinal Chemistry, 12:2727-2740. ★Equal contributors.
13. Ziarek, J.J. & Volkman, B.F. 2012. NMR in the analysis of functional chemokine interactions and drug discovery. Drug Discovery Today: Technologies, 9:e293-e299.
12. Takekoshi, T., Ziarek, J.J., Volkman, B.F. & Hwang, S.T. 2012. A locked, dimeric CXCL12 variant effectively inhibits pulmonary metastasis of CXCR4-expressing melanoma cells due to enhanced serum stability. Molecular Cancer Therapeutics, 11:2516-2525.
11. Mysinger, M.M.★, Weiss, D.R.★, Ziarek, J.J.★, Gravel, S., Doak, A.K., Karpiak, J., Heveker, N., Shoichet, B.K. & Volkman, B.F. 2012. Structure-based ligand discovery for chemokine receptor CXCR4. Proceedings of the National Academy of Sciences of the United States of America, 109: 5517-5522. ★Equal contributors.
10. Love, M., Sandberg, J.L., Ziarek, J.J., Rode, R.R., Gerarden, K.P., Jensen, D.R., McCastlin, D., Peterson, F.C. & Veldkamp, C.T. 2012. Solution structure of CCL21 and identification of a putative CCR7 binding site. Biochemistry, 51(3): 733-735.
9. Ziarek, J.J., Peterson, F.C., Lytle, B.L. & Volkman, B.F. 2011. Chapter ten: Binding site identification and structure determination of protein-ligand complexes by NMR. Methods in Enzymology, 493:241-275.
8. Drury, L.D.★, Ziarek, J.J.★, Gravel, S., Veldkamp, C.T., Takekoshi, T., Hwang, S.T., Heveker, N., Volkman, B.F. & Dwinell, M.B. 2011. Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways. Proceedings of the National Academy of Sciences of the United States of America, 108: 17655-17660. ★Equal contributors.
7. Saini, V., Staren, D.M., Ziarek, J.J., Nashaat, Z.N., Campbell, E.M., Volkman, B.F., Marchese, A. & Majetschak, M. 2011. The CXC chemokine receptor 4 ligands ubiquitin and stromal-cell derived factor-1α function through distinct receptor interactions. Journal of Biological Chemistry, 286: 33466-33477.
6. Ziarek, J.J., Heroux, M.S., Veldkamp, C.T., Peterson, F.C. & Volkman, B.F. 2011. Sulfotyrosine recognition as marker for druggable sites in the extracellular space. International Journal of Molecular Sciences, 12(6), 3740-3756.
5. Ziarek, J.J., Nihongi, A., Nagai, T., Uttieri, M., Zambianchi, E., & Stricker, J.R. 2011. Seasonal adaptations of Daphnia pulicaria swimming behaviour: the effect of water temperature. Hydrobiologia, 661: 317-327.
4. Nihongi, A., Ziarek, J.J., Nagai, T., Uttieri, M., Zambianchi, E. & Strickler, J.R. 2011. Daphnia pulicaria hijacked by Vibrio cholera: Altered swimming behaviour and predation risk Implications. In: Zooplankton and Phytoplankton. Ed: Katell, G. Nova Science Publishers.
3. Veldkamp, C.T., Ziarek, J.J., Peterson, F.C., Chen, Y. & Volkman, B.F. 2010. Targeting SDF-1/CXCL12 with a ligand that prevents activation of CXCR4 through structure based drug design. Journal of the American Chemical Society, 132: 7242-7243.
2. Veldkamp, C.T., Ziarek, J.J., Su, J., Basnet, H., Lennertz, R., Weiner, J.J., Peterson, F.C., Baker, J.E. & Volkman, B.F. 2009. Monomeric structure of the cardioprotective chemokine SDF-1/CXCL12. Protein Science, 18:1359-1369.
1. Strickler, J.R., Udvadia, A.J., Marino, J., Radabaugh, N., Ziarek, J.J., & Nihongi, A. 2005. Visibility as a factor in the copepod – planktivorous fish relationship. Scientia Marina, 69(Suppl. 1):111-124.